ABSTRACT This paper addresses the different methods of estimation of the unknown parameters of a two-parameter unit-logistic distribution from the frequentist point of view. We briefly describe different approaches, namely, maximum likelihood estimators, percentile based estimators, least squares estimators, maximum product of spacings estimators, methods of minimum distances: Cramér-von Mises, AndersonDarling and four variants of Anderson-Darling. Monte Carlo simulations are performed to compare the performances of the proposed methods of estimation for both small and large samples. The performances of the estimators have been compared in terms of their relative bias, root mean squared error, average absolute difference between the theoretical and empirical estimate of the distribution functions and the maximum absolute difference between the theoretical and empirical distribution functions using simulated samples. Also, for each method of estimation, we consider the interval estimation using the Bootstrap confidence interval and calculate the coverage probability and the average width of the Bootstrap confidence intervals. Finally, two real data sets have been analyzed for illustrative purposes.